Article
Skeletal dysplasias and the osteoarthritic phenotype.
Best practice & research. Clinical rheumatology - 1 Dec 2003
Williams Charlene J, Jimenez Sergio A
Abstract excerpt
In contrast to late-onset osteoarthritis (OA), the appearance of precocious OA has historically been recognized as a particularly aggressive form of the disorder that is frequently inherited as a Mendelian trait. In general, precocious OA appears as a consequence of many skeletal dysplasias, which, although individually rare, comprise a sizable population of patients when viewed in toto. In these patients the...
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