Article
Notch signaling in osteoblasts.
Science signaling - 29 Apr 2008
Canalis Ernesto
Abstract excerpt
Bone remodeling is the result of the coordinated activity of osteoblasts, which form new matrix, and osteoclasts, which resorb bone. Notch proteins are single-pass transmembrane receptors that determine cell fate. Recent gain-of-function and loss-of-function experiments reveal a suppressive effec...
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