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Article

APOE/C1/C4/C2 gene cluster genotypes, haplotypes and lipid levels in prospective coronary heart disease risk among UK healthy men.

Molecular medicine (Cambridge, Mass.) - 1 Jan 2000

Ken-Dror Gie, Talmud Philippa J, Humphries Steve E, Drenos Fotios

Abstract excerpt

The role of common APOE variants on plasma lipids, particularly low density lipoprotein (LDL) levels, and coronary heart disease (CHD) risk is well known; the influence of variation in the other nearby apolipoprotein genes APOC1, APOC4 and APOC2 is unclear. This study examines the association between APOE/C1/C4/C2 gene cluster variation using tagging SNPs and plasma lipid concentration along with risk of CHD in a...

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Source

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Identifiers

PMID: 20498921
DOI: 10.2119/molmed.2010.00044
PMCID: PMC2935949

Genes

APOE
APOC1
APOC2
APOC4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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