Article
Genetic variants at newly identified lipid loci are associated with coronary heart disease in a Chinese Han population.
PloS one - 1 Jan 2011
Zhou Li, Ding Hu, Zhang Xiaomin, He Meian, Huang Suli, Xu Yujun, Shi Ying, Cui Guanglin, Cheng Longxian, Wang Qing K, Hu Frank B, Wang Daowen, Wu Tangchun
Abstract excerpt
BACKGROUND: Recent genome-wide association studies (GWAS) have mapped several novel loci influencing blood lipid levels in Caucasians. We sought to explore whether the genetic variants at newly identified lipid-associated loci were associated with CHD susceptibility in a Chinese Han population. METHODOLOGY/PRINCIPAL FINDINGS: We conducted a two-stage case-control study in a Chinese Han population. The...
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