Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Candidate gene genotypes, along with conventional risk factor assessment, improve estimation of coronary heart disease risk in healthy UK men.

Clinical chemistry - 1 Jan 2007

Humphries Steve E, Cooper Jackie A, Talmud Philippa J, Miller George J

Abstract excerpt

BACKGROUND: One of the aims of cardiovascular genetics is to test the efficacy of the use of genetic information to predict cardiovascular risk. We therefore investigated whether inclusion of a set of common variants in candidate genes along with conventional risk factor (CRF) assessment enhanced coronary heart disease (CHD)-risk algorithms. METHODS: We followed middle-aged men in the prospective Northwick Park...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Coronary Disease
Share to False Positive Reactions

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Multivariate Analysis

Share to Predictive Value of Tests

Share to Reference Values

Share to ROC Curve

Share to Smoking

Share to United Kingdom

Source

Identifiers

PMID: 17130180
DOI: 10.1373/clinchem.2006.074591

Genes

LPL
APOA4
APOE
PECAM1
UCP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Candidate gene genotypes, along with conventional risk factor assessment, improve estimation of coronary heart disease risk in healthy UK men.PMID 17130180Read ↗

Chromosome 9p21.3 coronary heart disease locus genotype and prospective risk of CHD in healthy middle-aged men.Semantic proximity Read ↗

Assessment of the clinical utility of adding common single nucleotide polymorphism genetic scores to classical risk factor algorithms in coronary heart disease risk prediction in UK men.Semantic proximity Read ↗

How close are we to implementing a genetic risk score for coronary heart disease?Semantic proximity Read ↗

Integration of biomarker polygenic risk score improves prediction of coronary heart disease in UK Biobank and FinnGenSemantic proximity Read ↗

An integrated polygenic and clinical risk tool enhances coronary artery disease predictionSemantic proximity Read ↗

Cardiovascular disease risk prediction using genetic information (gene scores): is it really informative?Semantic proximity Read ↗

Genomic prediction of coronary heart disease.Semantic proximity Read ↗

Use of polygenic risk scores and other molecular markers to enhance cardiovascular risk prediction: prospective cohort study and modelling analysisSemantic proximity Read ↗

Genetic risk prediction and a 2-stage risk screening strategy for coronary heart disease.Semantic proximity Read ↗

Prediction of cardiovascular disease outcomes and established cardiovascular risk factors by genome-wide association markers.Semantic proximity Read ↗

Prediction of Coronary Artery Disease and Major Adverse Cardiovascular Events Using Clinical and Genetic Risk Scores for Cardiovascular Risk Factors.Semantic proximity Read ↗

Literature-based genetic risk scores for coronary heart disease: the Cardiovascular Registry Maastricht (CAREMA) prospective cohort study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.