Article
APOE genotype, lipids, and coronary heart disease risk: a prospective population study.
Archives of internal medicine - 10 Aug 2009
Ward Heather, Mitrou Panagiota N, Bowman Richard, Luben Robert, Wareham Nicholas J, Khaw Kay-Tee, Bingham Sheila
Abstract excerpt
BACKGROUND: The risk of coronary heart disease (CHD) may be related to genetic mutations in the production of apolipoprotein E via alterations to the metabolism of CHD-related blood lipids such as low-density lipoprotein cholesterol and triglycerides. METHODS: The relationship between APOE genotype (*E3/*E3, *E3/*E4, *E2/*E3, *E4/*E4, *E2/*E4, and *E2/*E2) and fatal and nonfatal CHD was examined among 10 035 men...
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