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GPI-anchored Gas1 protein regulates cytosolic proteostasis in yeast

2023-05-27

Abstract excerpt

Decline in protein homeostasis (proteostasis) is a hallmark of cellular aging and aging-related diseases. Maintaining a balanced proteostasis requires a complex network of molecular machineries that govern protein synthesis, folding, localization, and degradation. Under proteotoxic stress, misfolded proteins that accumulate in cytosol can be imported into mitochondria for degradation via ‘mitochondrial as guardian...

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Literature Corpus work
d8b6fc7e-882b-5a36-9c8e-f9f6ee059c32
DOI
10.1101/2023.05.26.542479
Open publication

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GPI-anchored Gas1 protein regulates cytosolic proteostasis in yeastDOI 10.1101/2023.05.26.542479
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