Article
Alg13p, the catalytic subunit of the endoplasmic reticulum UDP-GlcNAc glycosyltransferase, is a target for proteasomal degradation.
Molecular biology of the cell - 1 May 2008
Averbeck Nicole, Gao Xiao-Dong, Nishimura Shin-Ichiro, Dean Neta
Abstract excerpt
The second step of dolichol-linked oligosaccharide synthesis in the N-linked glycosylation pathway at the endoplasmic reticulum (ER) membrane is catalyzed by an unusual hetero-oligomeric UDP-N-acetylglucosamine transferase that in most eukaryotes is comprised of at least two subunits, Alg13p and Alg14p. Alg13p is the cytosolic and catalytic subunit that is recruited to the ER by the membrane protein Alg14p. We...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
