Article
The expression of twisted gastrulation in postnatal mouse brain and functional implications.
Neuroscience - 25 Aug 2010
Sun M, Forsman C, Sergi C, Gopalakrishnan R, O'Connor M B, Petryk A
Abstract excerpt
Twisted gastrulation (TWSG1), an extracellular regulator of bone morphogenetic protein (BMP) signaling, is critical for embryonic brain development. Mice deficient in TWSG1 have abnormal forebrain development manifesting as holoprosencephaly. The expression and potential roles of TWSG1 in postnatal brain development are less well understood. We show that Twsg1 is expressed in the adult mouse brain in the choroid...
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