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Expression and function of the P2X(7) purinergic receptor in patients with systemic lupus erythematosus and rheumatoid arthritis.

Human immunology - 1 Aug 2010

Portales-Cervantes Liliana, Niño-Moreno Perla, Doníz-Padilla Lesly, Baranda-Candido Lourdes, García-Hernández Mariana, Salgado-Bustamante Mariana, González-Amaro Roberto, Portales-Pérez Diana

Abstract excerpt

Because the synthesis of pro-inflammatory cytokines and apoptosis of lymphoid cells can be induced through P2X(7), we decided to study its expression, function (apoptosis, shedding of CD62L and synthesis of IL-1beta induced by ATP) and genetic polymorphisms (1513 AC and -762 T/C) in peripheral blood mononuclear cells from 101 patients with systemic lupus erythematosus (SLE), 122 with rheumatoid arthritis (RA) and...

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PMID: 20493226
DOI: 10.1016/j.humimm.2010.05.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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