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Article

Overexpression of STARD3 in human monocyte/macrophages induces an anti-atherogenic lipid phenotype.

Clinical science (London, England : 1979) - 22 Jun 2010

Borthwick Faye, Allen Anne-Marie, Taylor Janice M, Graham Annette

Abstract excerpt

Dysregulated macrophage cholesterol homoeostasis lies at the heart of early and developing atheroma, and removal of excess cholesterol from macrophage foam cells, by efficient transport mechanisms, is central to stabilization and regression of atherosclerotic lesions. The present study demonstrates that transient overexpression of STARD3 {START [StAR (steroidogenic acute regulatory protein)-related lipid...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20491656
DOI: 10.1042/CS20100266
PMCID: PMC2891001

Genes

STARD3
ABCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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