Article

The sterol transporter STARD3 transports sphingosine at ER-lysosome contact sites

2023-09-18

Abstract excerpt

<h4>Summary</h4> Sphingolipids are important structural components of membranes. Additionally, simple sphingolipids such as sphingosine are highly bioactive and participate in complex subcellular signaling. Sphingolipid deregulation is associated with many severe diseases including diabetes, Parkinson’s and cancer. Here, we focus on how sphingosine, generated from sphingolipid catabolism in late endosomes/lysosom...

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Literature Corpus work: 00ecb1cc-05e6-56f4-8d54-86a5b3e47bbf
DOI: 10.1101/2023.09.18.557036

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