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Article

Hidden features: CD36/SR-B2, a master regulator of macrophage phenotype/function through metabolism.

Frontiers in immunology - 1 Jan 2024

Chen Yuge, Zhang Xuejia, Huang Shengbin, Febbraio Maria

Abstract excerpt

Once thought to be in a terminally differentiated state, macrophages are now understood to be highly pliable, attuned and receptive to environmental cues that control and align responses. In development of purpose, the centrality of metabolic pathways has emerged. Thus, macrophage inflammatory or reparative phenotypes are tightly linked to catabolic and anabolic metabolism, with further fine tuning of specific...

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Share to Adipokines, Inflammation, and Metabolic Diseases
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39742252
DOI: 10.3389/fimmu.2024.1468957
PMCID: PMC11685046

Genes

CD36

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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