Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

p53 and PI3K/AKT signalings are up-regulated in flies with defects in the THO complex.

Molecules and cells - 1 Mar 2013

Moon Sungjin, Chung Yun Doo

Abstract excerpt

The THO complex (THO) is an evolutionary conserved protein required for the formation of export-competent mRNP. The growing evidence indicates that the metazoan THO plays important roles in cell differentiation and cellular stress response. But the underlying mechanisms are poorly understood. Herein we examined the relevance of THO to cellular signaling pathways involved in cell differentiation and cellular...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Protein Subunits
Share to Pigmentation
Share to Body Size

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Multiprotein Complexes

Share to Proto-Oncogene Proteins c-akt

Share to Retinal Degeneration

Share to Spermatogenesis

Share to Testis

Source

Open in PubMed Open full text

Identifiers

PMID: 23475424
DOI: 10.1007/s10059-013-0009-x
PMCID: PMC3887910

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

p53 and PI3K/AKT signalings are up-regulated in flies with defects in the THO complex.PMID 23475424Read ↗

The THO complex as a key mRNP biogenesis factor in development and cell differentiation.Semantic proximity Read ↗

The Caenorhabditis elegans THO complex is required for the mitotic cell cycle and development.Semantic proximity Read ↗

The THO complex in Schizosaccharomyces pombe-dissecting the composition and functional hierarchy.Semantic proximity Read ↗

An ataxia-telangiectasia-mutated (ATM) kinase mediated response to DNA damage down-regulates the mRNA-binding potential of THOC5.Semantic proximity Read ↗

Ectopic expression of human p53 inhibits entry into S phase and induces apoptosis in the Drosophila eye imaginal disc.Semantic proximity Read ↗

Examining the potential involvement of NONO in TDP-43 proteinopathy in <i>Drosophila</i>Semantic proximity Read ↗

Sex specific systemic effects of <i>sev-Gal4</i> driven activated Ras expression mediated through hnRNPs in <i>Drosophila</i>Semantic proximity Read ↗

Drosophila p53 integrates the antagonism between autophagy and apoptosis in response to stressSemantic proximity Read ↗

Examining the potential involvement of NONO in TDP-43 proteinopathy in DrosophilaSemantic proximity Read ↗

Over-expression of transglutaminase in the Drosophila eye imaginal disc induces a rough eye phenotype.Semantic proximity Read ↗

Expression of rck/p54, a DEAD-box RNA helicase, in gametogenesis and early embryogenesis of mice.Semantic proximity Read ↗

Mutations of t-complex testis expressed gene 5 transcripts in the testis of sterile t-haplotype mutant mouse.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.