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Article

Interdomain interactions control Ca2+-dependent potentiation in the cation channel TRPV4.

PloS one - 11 May 2010

Strotmann Rainer, Semtner Marcus, Kepura Frauke, Plant Tim D, Schöneberg Torsten

Abstract excerpt

Several Ca(2+)-permeable channels, including the non-selective cation channel TRPV4, are subject to Ca(2+)-dependent facilitation. Although it has been clearly demonstrated in functional experiments that calmodulin (CaM) binding to intracellular domains of TRP channels is involved in this process...

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Source

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Identifiers

PMID: 20485495
DOI: 10.1371/journal.pone.0010580
PMCID: PMC2867956

Genes

TRPV4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-20485495-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Interdomain interactions control Ca2+-dependent potentiation in the cation channel TRPV4.PMID 20485495Read ↗

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