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Article

Integrative binding sites within intracellular termini of TRPV1 receptor.

PloS one - 1 Jan 2012

Grycova Lenka, Holendova Blanka, Bumba Ladislav, Bily Jan, Jirku Michaela, Lansky Zdenek, Teisinger Jan

Abstract excerpt

TRPV1 is a nonselective cation channel that integrates wide range of painful stimuli. It has been shown that its activity could be modulated by intracellular ligands PIP2 or calmodulin (CaM). The detailed localization and description of PIP2 interaction sites remain unclear. Here, we used synthesized peptides and purified fusion proteins of intracellular regions of TRPV1 expressed in E.coli in combination with...

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Identifiers

PMID: 23119017
DOI: 10.1371/journal.pone.0048437
PMCID: PMC3485206

Genes

TRPV1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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