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Article

Complement component C5a activates ICAM-1 expression on human choroidal endothelial cells.

Investigative ophthalmology & visual science - 1 Oct 2010

Skeie Jessica M, Fingert John H, Russell Stephen R, Stone Edwin M, Mullins Robert F

Abstract excerpt

PURPOSE: The complement system plays a crucial role in the progression of age-related macular degeneration (AMD). In this study, the authors sought to evaluate the pathophysiologic roles of complement components C3a and C5a in the human choroid in AMD. METHODS: Human RPE/choroid was assayed for t...

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Share to Cell Movement
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Intercellular Adhesion Molecule-1

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Source

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Identifiers

PMID: 20484595
DOI: 10.1167/iovs.10-5322
PMCID: PMC3066598

Genes

RPE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20484595-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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