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Article

Molecular response of chorioretinal endothelial cells to complement injury: implications for macular degeneration

13 Nov 2015

Abstract excerpt

Age-related macular degeneration (AMD) is a common, blinding disease of the elderly in which macular photoreceptor cells, retinal pigment epithelium and choriocapillaris endothelial cells ultimately degenerate. Recent studies have found that degeneration of the choriocapillaris occurs early in this disease and that endothelial cell drop-out is concomitant with increased deposition of the complement membrane...

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PMID: 26564985
DOI: 10.1002/path.4669

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