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Article

APOE epsilon4 and the cognitive genetics of multiple sclerosis.

Neurology - 18 May 2010

Ghaffar O, Reis M, Pennell N, O'Connor P, Feinstein A

Abstract excerpt

BACKGROUND: Evidence linking APOE to myelin repair, neuronal plasticity, and cerebral inflammatory processes suggests that it may be relevant in multiple sclerosis (MS). The purpose of this study was to determine whether the epsilon4 allele of APOE is associated with cognitive deficits in patients with MS. METHOD: Using a case-control design, 50 patients with MS with the epsilon4 allele (epsilon4+) and 50...

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Source

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Identifiers

PMID: 20479360
DOI: 10.1212/WNL.0b013e3181e074a7
PMCID: PMC2875133

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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