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Article

The association of apolipoprotein E (ApoE) genotype and cognitive outcomes in multiple sclerosis; a systematic review and meta-analysis.

Multiple sclerosis and related disorders - 1 Sept 2022

Naseri Amirreza, Baghernezhad Kosar, Seyedi-Sahebari Sepideh, Alhoseini Seyed Ardalan, Gholipour-Khalili Elnaz, Zafarani Fatemeh, Talebi Mahnaz

Abstract excerpt

BACKGROUND: Multiple sclerosis (MS) is a neuroinflammatory disorder commonly seen in young female adults. Cognitive impairment is one of the widespread symptoms of MS. In recent years multiple studies sought the possible risk factors for MS-related cognitive deficit. Apolipoprotein E (ApoE) genotype is one of the genetic factors which correlated significantly with cognitive status and it is a well-known risk...

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Identifiers

PMID: 35803087
DOI: 10.1016/j.msard.2022.104011

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