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Article

APOE epsilon 4 allele is associated with cognitive impairment in patients with multiple sclerosis.

Neurology - 15 Jan 2008

Shi J, Zhao C B, Vollmer T L, Tyry T M, Kuniyoshi S M

Abstract excerpt

BACKGROUND: The role of apolipoprotein E (APOE) polymorphism has been well recognized in other cognitive neurodegenerative disorders, such as Alzheimer disease. Its role in multiple sclerosis (MS) is less clear, though studies indicate that 40% to 60% of patients with MS have evidence of cognitiv...

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Source

Identifiers

PMID: 17460153
DOI: 10.1212/01.wnl.0000264004.62612.44

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Prepared record publication-17460153-2026-09-05.1. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 5 Sept 2026.

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APOE epsilon 4 allele is associated with cognitive impairment in patients with multiple sclerosis.PMID 17460153Read ↗

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