Article
Characterization of yeast translation initiation factor 1A and cloning of its essential gene.
The Journal of biological chemistry - 29 Sept 1995
Wei C L, Kainuma M, Hershey J W
Abstract excerpt
Translation initiation factor eIF1A is required in vitro for maximal rates of protein synthesis in mammalian systems. It functions primarily by dissociating ribosomes and stabilizing 40 S preinitiation complexes. To better elucidate its precise role in promoting the translation initiation process, the yeast form of eIF1A has been identified in Saccharomyces cerevisiae and purified to homogeneity on the basis of...
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