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Article

Established genetic risk factors do not distinguish early and later onset Crohn's disease.

Inflammatory bowel diseases - 1 Oct 2009

Essers Jonah B, Lee Jessica J, Kugathasan Subra, Stevens Christine R, Grand Richard J, Daly Mark J

Abstract excerpt

BACKGROUND: Early-onset disease is frequently examined in genetic studies because it is presumed to contain a more severe subset of patients under a higher influence of genetic effects. In light of the dramatic success of Crohn's disease (CD) gene discovery efforts, we aimed to characterize the contribution of established common risk variants to pediatric CD. METHODS: Using 35 confirmed CD risk alleles, we...

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Identifiers

PMID: 19322901
DOI: 10.1002/ibd.20922
PMCID: PMC2768775

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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