Article
Role of genetics in pediatric inflammatory bowel disease.
Inflammatory bowel diseases - 1 Oct 2014
Okou David T, Kugathasan Subra
Abstract excerpt
Inflammatory bowel disease (IBD), encompassing Crohn's disease (CD), ulcerative colitis (UC), and unclassified IBD, is characterized by chronic intestinal inflammation and has a multifactorial etiology with complex interactions between genetic and environmental factors. The genetics of IBD are believed to be common and complex with over 163 associated genetic loci. However, the genetic contribution of the...
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