Article
Evidence for an influence of chemokine ligand 3-like 1 (CCL3L1) gene copy number on susceptibility to rheumatoid arthritis.
Annals of the rheumatic diseases - 1 Mar 2008
McKinney C, Merriman M E, Chapman P T, Gow P J, Harrison A A, Highton J, Jones P B B, McLean L, O'Donnell J L, Pokorny V, Spellerberg M, Stamp L K, Willis J, Steer S, Merriman T R
Abstract excerpt
OBJECTIVE: There is increasing evidence that gene copy-number variation influences phenotypic variation. Chemokine ligand 3-like 1 (CCL3L1) is encoded by a variable copy-number gene, and binds to several pro-inflammatory cytokine receptors, including chemokine receptor 5 (CCR5). Considering lymph...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
