Article
A common polymorphism in the 3'-UTR of the NOS1 gene was associated with completed suicides in Japanese male population.
Progress in neuro-psychopharmacology & biological psychiatry - 16 Aug 2010
Cui Huxing, Supriyanto Irwan, Asano Migiwa, Ueno Yasuhiro, Nagasaki Yasushi, Nishiguchi Naoki, Shirakawa Osamu, Hishimoto Akitoyo
Abstract excerpt
BACKGROUND: Suicidal behavior has been widely accepted as familial. Its transmission cannot be explained by the transmission of psychiatric disorder alone and seems to be partly explained by the transmission of impulsive-aggressive behavior. Studies in laboratory animal have shown that mice lacking NOS1 manifest significant aggressive behavior. Further, several polymorphisms of neuronal nitric oxide synthase...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.