Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CD38 expression, function, and gene resequencing in a human lymphoblastoid cell line-based model system.

Leukemia & lymphoma - 1 Jul 2010

Hartman William R, Pelleymounter Linda L, Moon Irene, Kalari Krishna, Liu Mohan, Wu Tse-Yu, Escande Carlos, Nin Veronica, Chini Eduardo N, Weinshilboum Richard M

Abstract excerpt

CD38 is an ecto-enzyme that hydrolyzes NAD. Its expression is a prognostic marker for chronic lymphocytic leukemia. We have characterized individual variation in CD38 expression in lymphoblastoid cell lines from 288 healthy subjects of three ethnicities. Expression varied widely, with significant differences among ethnic groups, and was correlated significantly with CD38 enzymatic activity and protein levels. The...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to ADP-ribosyl Cyclase 1
Share to Antimetabolites, Antineoplastic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytarabine

Share to Deoxycytidine

Share to Electrophoretic Mobility Shift Assay

Share to Gemcitabine

Share to Lymphocytes

Share to Oligonucleotide Array Sequence Analysis

Source

Open in PubMed Open full text

Identifiers

PMID: 20470215
DOI: 10.3109/10428194.2010.483299
PMCID: PMC2892000

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CD38 expression, function, and gene resequencing in a human lymphoblastoid cell line-based model system.PMID 20470215Read ↗

Bio-informatic Analysis of Missense Single Nucleotide Polymorphisms (SNPs) in Human CD38 Gene Associated with B-Chronic Lymphocytic LeukemiaSemantic proximity Read ↗

CD38 gene polymorphisms contribute to genetic susceptibility to B-cell chronic lymphocytic leukemia: evidence from two case-control studies in Polish Caucasians.Semantic proximity Read ↗

The Pharmacology of CD38/NADase: An Emerging Target in Cancer and Diseases of AgingSemantic proximity Read ↗

<i>ATM, CTLA4, MNDA</i>, and<i>HEM1</i>in High versus Low CD38–Expressing B-Cell Chronic Lymphocytic LeukemiaSemantic proximity Read ↗

The enzymatic activities of CD38 enhance CLL growth and trafficking: implications for therapeutic targeting.Semantic proximity Read ↗

Large-Scale Analysis of DNA Methylation In Chronic Lymphocytic LeukemiaSemantic proximity Read ↗

Highly purified CD38+ and CD38− sub-clones derived from the same chronic lymphocytic leukemia patient have distinct gene expression signatures despite their monoclonal originSemantic proximity Read ↗

The human CD38 gene: polymorphism, CpG island, and linkage to the CD157 (BST-1) gene.Semantic proximity Read ↗

Whole-exome sequencing identifies a CD38 variant in a Chinese family with Hodgkin’s lymphomaSemantic proximity Read ↗

CD38 genotype-dependent regulation of CD44 and TP53 links genetic variation to aggressive phenotype in chronic lymphocytic leukemia.Semantic proximity Read ↗

CD38 gene polymorphism and risk of chronic lymphocytic leukemia.Semantic proximity Read ↗

Population variability in CD38 activity: correlation with age and significant effect of TNF-α -308G>A and CD38 184C>G SNPs.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.