Article
CD38 gene polymorphism and risk of chronic lymphocytic leukemia.
Leukemia research - 1 Oct 2012
Abramenko Iryna V, Bilous Nadiia I, Pleskach Gleb V, Chumak Anatoliy A, Kryachok Iryna A, Martina Zoya V, Dyagil Iryna S
Abstract excerpt
rs6449182 CD38 gene polymorphism was determined by polymerase chain reaction with restriction of products in 328 chronic lymphocytic leukemia (CLL) patients and 271 age- and sex-matched controls. An association between GG genotype and CLL risk was found in the whole group of patients (OR=2.12; p=0.009) and in patients with unmutated immunoglobulin heavy chain variable genes (OR=2.17; p=0.011) comparing to the...
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