Article
Large-Scale Analysis of DNA Methylation In Chronic Lymphocytic Leukemia
1 Oct 2009
Abstract excerpt
AIMS: B-cell chronic lymphocytic leukemia (CLL) is a heterogeneous malignancy that clinically ranges from indolent to rapidly progressive. CLL, like other cancers, can be affected by epigenetic alterations. MATERIALS & METHODS: A microarray discovery-based study was initiated to determine DNA methylation in CLL cases with a range of CD38 expression (1–92%). RESULTS: Many loci were either methylated or...
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