Article
The miR-143-<i>adducin3</i> pathway is essential for cardiac chamber morphogenesis
11 May 2010
Abstract excerpt
Discovering the genetic and cellular mechanisms that drive cardiac morphogenesis remains a fundamental goal, as three-dimensional architecture greatly impacts functional capacity. During development, accurately contoured chambers balloon from a primitive tube in a process characterized by regional changes in myocardial cell size and shape. How these localized changes are achieved remains elusive. Here, we show in...
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