Article
microRNA-133a regulates cardiomyocyte proliferation and suppresses smooth muscle gene expression in the heart.
Genes & development - 1 Dec 2008
Liu Ning, Bezprozvannaya Svetlana, Williams Andrew H, Qi Xiaoxia, Richardson James A, Bassel-Duby Rhonda, Olson Eric N
Abstract excerpt
MicroRNAs (miRNAs) modulate gene expression by inhibiting mRNA translation and promoting mRNA degradation, but little is known of their potential roles in organ formation or function. miR-133a-1 and miR-133a-2 are identical, muscle-specific miRNAs that are regulated during muscle development by t...
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