Article
santa and valentine pattern concentric growth of cardiac myocardium in the zebrafish.
Development (Cambridge, England) - 1 Aug 2006
Mably John D, Chuang Lesley P, Serluca Fabrizio C, Mohideen Manzoor-Ali P K, Chen Jau-Nian, Fishman Mark C
Abstract excerpt
During embryogenesis, the myocardial layer of the primitive heart tube grows outward from the endocardial-lined lumen, with new cells added to generate concentric thickness to the wall. This is a key evolutionary step, demarcating vertebrates from more primitive chordates, and is essential for normal cardiac function. Zebrafish embryos with the recessive lethal mutations santa (san) and valentine (vtn) do not...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.