Article
Association of Egr3 genetic polymorphisms and coronary artery disease in the Uygur and Han of China.
Lipids in health and disease - 21 May 2014
Li Xia, Ma Yi-Tong, Xie Xiang, Yang Yi-Ning, Ma Xiang, Zheng Ying-Ying, Pan Shuo, Liu Fen, Chen Bang-Dang
Abstract excerpt
BACKGROUND: Endothelial cell activation and dysfunction are the foundation of atherosclerosis, including coronary artery disease (CAD). Endothelial cell activation is mediated by the level of gene transcription. Early growth response 3 (Egr3) is a critical determinant of vascular endothelial growth factor (VEGF) signalling in activated endothelial cells. If endothelial cells are excessively activated, it may lead...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
