Article
Interaction between MMP-9 gene polymorphisms and smoking in relation to myocardial infarction in a Uighur population.
Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis - 1 Jan 2000
Wang Lei, Ma Yi-Tong, Xie Xiang, Yang Yi-Ning, Fu Zhen-Yan, Li Xiao-Mei, Liu Fen, Huang Ying, Ma Xiang, Chen Bang-Dang, Yuan Shan, Sun Ming-Hui, Peng Xiao, Wang Bao-Zhu
Abstract excerpt
OBJECTIVES: Matrix metalloproteinase 9 (MMP-9) plays a pivotal role in early atherosclerosis, vascular remodeling, and development of arterial plaque rupture. The potentially functional MMP-9 gene polymorphism may contribute to the susceptibility of myocardial infarction (MI). We aimed to investigate the association between the interaction of 2 single-nucleotide polymorphisms ([SNPs] -1562C>T and R279Q) of the...
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