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Article

Epidermal growth factor receptor and K-RAS status in two cohorts of squamous cell carcinomas.

BMC cancer - 11 May 2010

Van Damme Nancy, Deron Philippe, Van Roy Nadine, Demetter Pieter, Bols Alain, Van Dorpe Jo, Baert Filip, Van Laethem Jean-Luc, Speleman Franki, Pauwels Patrick, Peeters Marc

Abstract excerpt

BACKGROUND: With the availability of effective anti-EGFR therapies for various solid malignancies, such as non-cell small lung cancer, colorectal cancer and squamous cell carcinoma of the head and neck, the knowledge of EGFR and K-RAS status becomes clinically important. The aim of this study was to analyse EGFR expression, EGFR gene copy number and EGFR and K-RAS mutations in two cohorts of squamous cell...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Carcinoma, Squamous Cell

Share to Gene Amplification

Share to In Situ Hybridization, Fluorescence

Share to Proto-Oncogene Proteins p21(ras)

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Source

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Identifiers

PMID: 20459770
DOI: 10.1186/1471-2407-10-189
PMCID: PMC2887399

Genes

EGFR

Provenance

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