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Article

Epidermal growth factor receptor (EGFR) in salivary gland carcinomas: potentials as therapeutic target.

Oral oncology - 1 Oct 2012

Clauditz Till Sebastian, Gontarewicz Artur, Lebok Patrick, Tsourlakis Maria-Christina, Grob Tobias J, Münscher Adrian, Sauter Guido, Bokemeyer Carsten, Knecht Rainald, Wilczak Waldemar

Abstract excerpt

AIMS: Epidermal growth factor (EGFR) is involved in angiogenesis, cell differentiation, proliferation and progression of many cancers and is an important therapy target in lung and colorectal cancer. To determine the potential applicability of EGFR targeted therapies, EGFR status of over 800 salivary gland tumors of different entities were analyzed on DNA and protein level by FISH and IHC. MATERIALS AND METHODS:...

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Identifiers

PMID: 22694907
DOI: 10.1016/j.oraloncology.2012.05.005

Genes

EGFR

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