Article
Mds3 regulates morphogenesis in Candida albicans through the TOR pathway.
Molecular and cellular biology - 1 Jul 2010
Zacchi Lucia F, Gomez-Raja Jonatan, Davis Dana A
Abstract excerpt
The success of Candida albicans as a major human fungal pathogen is dependent on its ability to colonize and survive as a commensal on diverse mucosal surfaces. One trait required for survival and virulence in the host is the morphogenetic yeast-to-hypha transition. Mds3 was identified as a regulator of pH-dependent morphogenesis that functions in parallel with the classic Rim101 pH-sensing pathway. Microarray...
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