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Sdd3 regulates the biofilm formation of Candida albicans via the Rho1-PKC-MAPK pathway

17 Dec 2024

Abstract excerpt

ABSTRACT Candida albicans , the most frequently isolated fungal pathogen in humans, forms biofilms that enhance resistance to antifungal drugs and host immunity, leading to frequent treatment failure. Understanding the molecular mechanisms governing biofilm formation is crucial for developing anti-biofilm therapies. In this study, we conducted a genetic screen to identify novel genes that regulate biofilm...

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PMID: 39688394
DOI: 10.1128/mbio.03283-24

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