Article
Variants within the immunoregulatory CBLB gene are associated with multiple sclerosis.
Nature genetics - 1 Jun 2010
Sanna Serena, Pitzalis Maristella, Zoledziewska Magdalena, Zara Ilenia, Sidore Carlo, Murru Raffaele, Whalen Michael B, Busonero Fabio, Maschio Andrea, Costa Gianna, Melis Maria Cristina, Deidda Francesca, Poddie Fausto, Morelli Laura, Farina Gabriele, Li Yun, Dei Mariano, Lai Sandra, Mulas Antonella, Cuccuru Gianmauro, Porcu Eleonora, Liang Liming, Zavattari Patrizia, Moi Loredana, Deriu Elisa, Urru M Francesca, Bajorek Michele, Satta Maria Anna, Cocco Eleonora, Ferrigno Paola, Sotgiu Stefano, Pugliatti Maura, Traccis Sebastiano, Angius Andrea, Melis Maurizio, Rosati Giulio, Abecasis Gonçalo R, Uda Manuela, Marrosu Maria Giovanna, Schlessinger David, Cucca Francesco
Abstract excerpt
A genome-wide association scan of approximately 6.6 million genotyped or imputed variants in 882 Sardinian individuals with multiple sclerosis (cases) and 872 controls suggested association of CBLB gene variants with disease, which was confirmed in 1,775 cases and 2,005 controls (rs9657904, overa...
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