Article
Association of the CBLB gene with multiple sclerosis: new evidence from a replication study in an Italian population.
Journal of medical genetics - 1 Mar 2011
Corrado Lucia, Bergamaschi Laura, Barizzone Nadia, Fasano Maria Edvige, Guerini Franca R, Salvetti Marco, Galimberti Daniela, Benedetti Maria Donata, Leone Maurizio, D'Alfonso Sandra
Abstract excerpt
BACKGROUND: The T allele of rs9657904 within the CBLB gene was recently found to be significantly associated with multiple sclerosis (MS) in a genome-wide association study in Sardinia. OBJECTIVE: To replicate this association in an independent population with a different genetic background. METHODS: The rs9657904 variant was typed in a sample of 1435 cases and 1466 controls from the Italian mainland. RESULTS: It...
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