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Article

A comprehensive study of the association between the EGFR and ERBB2 genes and glioma risk.

Acta oncologica (Stockholm, Sweden) - 1 Aug 2010

Andersson Ulrika, Schwartzbaum Judith, Wiklund Fredrik, Sjöström Sara, Liu Yanhong, Tsavachidis Spyros, Ahlbom Anders, Auvinen Anssi, Collatz-Laier Helle, Feychting Maria, Johansen Christoffer, Kiuru Anne, Lönn Stefan, Schoemaker Minouk J, Swerdlow Anthony J, Henriksson Roger, Bondy Melissa, Melin Beatrice

Abstract excerpt

Glioma is the most common type of adult brain tumor and glioblastoma, its most aggressive form, has a dismal prognosis. Receptor tyrosine kinases such as the epidermal growth factor receptor (EGFR, ERBB2, ERBB3, ERBB4) family, and the vascular endothelial growth factor receptor (VEGFR), play a central role in tumor progression. We investigated the genetic variants of EGFR, ERBB2, VEGFR and their ligands, EGF and...

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Identifiers

PMID: 20446891
DOI: 10.3109/0284186X.2010.480980

Genes

EGFR
ERBB2
EGF
ERBB3
ERBB4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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