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Article

Genetic variation in the EGFR gene and the risk of glioma in a Chinese Han population.

PloS one - 1 Jan 2012

Hou Wu-Gang, Ai Wen-Bo, Bai Xiao-Guang, Dong Hai-Long, Li Zhen, Zhang Yuan-Qiang, Xiong Li-Ze

Abstract excerpt

Previous studies have shown that regulation of the epidermal growth factor gene (EGFR) pathway plays a role in glioma progression. Certain genotypes of the EGFR gene may be related to increased glioblastoma risk, indicating that germ line EGFR polymorphisms may have implications in carcinogenesis. To examine whether and how variants in the EGFR gene contribute to glioma susceptibility, we evaluated nine tagging...

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Identifiers

PMID: 22662167
DOI: 10.1371/journal.pone.0037531
PMCID: PMC3360779

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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