Article
EGFR as a clinical marker in glioblastomas and other gliomas.
The International journal of biological markers - 1 Jan 2018
Saadeh Fadi S, Mahfouz Rami, Assi Hazem I
Abstract excerpt
Epidermal growth factor receptor (EGFR) is a transmembrane glycoprotein and a member of the tyrosine kinase superfamily receptor. Gliomas are tumors originating from glial cells, which show a range of aggressiveness depending on grade and stage. Many EGFR gene alterations have been identified in gliomas, especially glioblastomas, including amplifications, deletions and single nucleotide polymorphisms (SNPs)....
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