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Article

Association between genetic variations of vascular endothelial growth factor receptor 2 and glioma in the Chinese Han population.

Journal of molecular neuroscience : MN - 1 Jul 2012

Chen Hongyan, Wang Weimin, Xingjie Zhao, Song Xiao, Fan Weiwei, Keke Zhou, Chen Gong, Zhao Yao, Mao Ying, Lu Daru

Abstract excerpt

Tumor angiogenesis, which is an important step in the development of cancer, is directly regulated by vascular endothelial growth factor receptor 2 (VEGFR-2). In this study, we examined the association of five potentially functional VEGFR-2 polymorphisms with glioma risk in a Chinese Han population. Three SNPs, rs2071559, rs7667298 and rs2305948, showed a statistically significant increased association with the...

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PMID: 22274884
DOI: 10.1007/s12031-012-9705-9

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