Article
Pre-diagnostic serum levels of EGFR and ErbB2 and genetic glioma risk variants: a nested case-control study.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Aug 2016
Späth Florentin, Andersson Ulrika, Dahlin Anna M, Langseth Hilde, Hovig Eivind, Johannesen Tom Børge, Grankvist Kjell, Björkblom Benny, Wibom Carl, Melin Beatrice
Abstract excerpt
Genetic variants have been associated with the risk of developing glioma, but functional mechanisms on disease phenotypic traits remain to be investigated. One phenotypic trait of glioblastoma is the mutation and amplification of the epidermal growth factor receptor (EGFR) gene. We investigated associations between pre-diagnostic serum protein concentrations of EGFR and ErbB2, both members of the EGFR family, and...
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