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Article

Genetic variations in EGF and EGFR and glioblastoma outcome.

Neuro-oncology - 1 Aug 2010

Sjöström Sara, Andersson Ulrika, Liu Yanhong, Brännström Thomas, Broholm Helle, Johansen Christoffer, Collatz-Laier Helle, Henriksson Roger, Bondy Melissa, Melin Beatrice

Abstract excerpt

Few prognostic factors have been associated with glioblastoma survival. We analyzed a complete tagging of the epidermal growth factor (EGF) and EGF receptor (EGFR) gene polymorphisms as potential prognostic factors. Thirty tagging single-nucleotide polymorphisms (SNPs) in EGF and 89 tagging SNPs in EGFR were analyzed for association with survival in 176 glioblastoma cases. Validation analyses were performed for 4...

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Identifiers

PMID: 20197289
DOI: 10.1093/neuonc/noq018
PMCID: PMC2940681

Genes

EGF
EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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