Article
Chromosome 7p11.2 (EGFR) variation influences glioma risk.
Human molecular genetics - 15 Jul 2011
Sanson Marc, Hosking Fay J, Shete Sanjay, Zelenika Diana, Dobbins Sara E, Ma Yussanne, Enciso-Mora Victor, Idbaih Ahmed, Delattre Jean-Yves, Hoang-Xuan Khe, Marie Yannick, Boisselier Blandine, Carpentier Catherine, Wang Xiao-Wei, Di Stefano Anna Luisa, Labussière Marianne, Gousias Konstantinos, Schramm Johannes, Boland Anne, Lechner Doris, Gut Ivo, Armstrong Georgina, Liu Yanhong, Yu Robert, Lau Ching, Di Bernardo Maria Chiara, Robertson Lindsay B, Muir Kenneth, Hepworth Sarah, Swerdlow Anthony, Schoemaker Minouk J, Wichmann H-Erich, Müller Martina, Schreiber Stefan, Franke Andre, Moebus Susanne, Eisele Lewin, Försti Asta, Hemminki Kari, Lathrop Mark, Bondy Melissa, Houlston Richard S, Simon Matthias
Abstract excerpt
While gliomas are the most common primary brain tumors, their etiology is largely unknown. To identify novel risk loci for glioma, we conducted genome-wide association (GWA) analysis of two case-control series from France and Germany (2269 cases and 2500 controls). Pooling these data with previously reported UK and US GWA studies provided data on 4147 glioma cases and 7435 controls genotyped for 424 460 common...
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