Article
Two independent variants of epidermal growth factor receptor associated with risk of glioma in a Korean population.
Scientific reports - 8 Nov 2022
Baek In Ki, Cheong Hyun Sub, Namgoong Seok, Kim Jeong-Hyun, Kang Seok-Gu, Yoon Seon-Jin, Kim Se Hoon, Chang Jong Hee, Kim Lyoung Hyo, Shin Hyoung Doo
Abstract excerpt
Gliomas are the most common primary tumors in the brain and spinal cord. In previous GWASs, SNPs in epidermal growth factor receptor (EGFR) have been reported as risk loci for gliomas. However, EGFR variants associated with gliomas in the Korean population remain unstudied. This study explored the association of EGFR SNPs with the risk of glioma. We genotyped 13 EGFR exon SNPs in a case-control study that...
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