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Article

Cloning and identification of tissue-specific expression of KCNN4 splice variants in rat colon.

American journal of physiology. Cell physiology - 1 Aug 2010

Barmeyer Christian, Rahner Christoph, Yang Youshan, Sigworth Frederick J, Binder Henry J, Rajendran Vazhaikkurichi M

Abstract excerpt

KCNN4 channels that provide the driving force for cAMP- and Ca(2+)-induced anion secretion are present in both apical and basolateral membranes of the mammalian colon. However, only a single KCNN4 has been cloned. This study was initiated to identify whether both apical and basolateral KCNN4 channels are encoded by the same or different isoforms. Reverse transcriptase-PCR (RT-PCR), real-time quantitative-PCR...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20445171
DOI: 10.1152/ajpcell.00091.2009
PMCID: PMC2928625

Genes

KCNN4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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