Article
Association of a polymorphic variant of the adiponectin gene with insulin resistance in african americans.
Clinical and translational science - 1 Dec 2008
Specchia Claudia, Scott Kathryn, Fortina Paolo, Devoto Marcella, Falkner Bonita
Abstract excerpt
Hypertension, type 2 diabetes, and obesity are common complex disorders that contribute to cardiovascular (CV) disease. Insulin resistance increases CV risk and is present in these disorders. Adiponectin, a protein secreted by adipocytes with metabolic and vascular protective effects, is lower in obesity and insulin resistance. Several single nucleotide polymorphisms (SNP) have been identified in the adiponectin...
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